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Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1

Cells have evolved mechanisms to protect, restart and repair perturbed replication forks, allowing full genome duplication, even under replication stress. Interrogating the interplay between nuclease-helicase Dna2 and Holliday junction (HJ) resolvase Yen1, we find the Dna2 helicase activity acts par...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Ölmezer, Gizem, Levikova, Maryna, Klein, Dominique, Falquet, Benoît, Fontana, Gabriele Alessandro, Cejka, Petr, Rass, Ulrich
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093310/
https://ncbi.nlm.nih.gov/pubmed/27779184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13157
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