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Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane

Rif1 is involved in telomere homeostasis, DNA replication timing, and DNA double-strand break (DSB) repair pathway choice from yeast to human. The molecular mechanisms that enable Rif1 to fulfill its diverse roles remain to be determined. Here, we demonstrate that Rif1 is S-acylated within its conse...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fontana, Gabriele A., Hess, Daniel, Reinert, Julia K., Mattarocci, Stefano, Falquet, Benoît, Klein, Dominique, Shore, David, Thomä, Nicolas H., Rass, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557901/
https://ncbi.nlm.nih.gov/pubmed/31182712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10349-z
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