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Sequence and structural patterns detected in entangled proteins reveal the importance of co-translational folding

Proteins must fold quickly to acquire their biologically functional three-dimensional native structures. Hence, these are mainly stabilized by local contacts, while intricate topologies such as knots are rare. Here, we reveal the existence of specific patterns adopted by protein sequences and struct...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baiesi, Marco, Orlandini, Enzo, Seno, Flavio, Trovato, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557820/
https://ncbi.nlm.nih.gov/pubmed/31182755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44928-3
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