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Folding Rate Optimization Promotes Frustrated Interactions in Entangled Protein Structures

Many native structures of proteins accomodate complex topological motifs such as knots, lassos, and other geometrical entanglements. How proteins can fold quickly even in the presence of such topological obstacles is a debated question in structural biology. Recently, the hypothesis that energetic f...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Norbiato, Federico, Seno, Flavio, Trovato, Antonio, Baiesi, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981561/
https://ncbi.nlm.nih.gov/pubmed/31892272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010213
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