Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights

Down Syndrome (DS) is the most common genetic cause of intellectual disability, in which an extra copy of human chromosome 21 (HSA21) affects regional DNA methylation profiles across the genome. Although DNA methylation has been previously examined at select regulatory regions across the genome in a...

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Bibliografische gegevens
Gepubliceerd in:Epigenetics
Hoofdauteurs: Laufer, Benjamin I., Hwang, Hyeyeon, Vogel Ciernia, Annie, Mordaunt, Charles E., LaSalle, Janine M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557615/
https://ncbi.nlm.nih.gov/pubmed/31010359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1609867
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