Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights

Down Syndrome (DS) is the most common genetic cause of intellectual disability, in which an extra copy of human chromosome 21 (HSA21) affects regional DNA methylation profiles across the genome. Although DNA methylation has been previously examined at select regulatory regions across the genome in a...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Epigenetics
Asıl Yazarlar: Laufer, Benjamin I., Hwang, Hyeyeon, Vogel Ciernia, Annie, Mordaunt, Charles E., LaSalle, Janine M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557615/
https://ncbi.nlm.nih.gov/pubmed/31010359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1609867
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