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Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages

The BTBR T(+)Itpr3(tf)/J (BTBR) mouse has been used as a complex genetic model of Autism Spectrum Disorders (ASD). While the specific mechanisms underlying BTBR behavioral phenotypes are poorly understood, prior studies have implicated profound differences in innate immune system control of pro-infl...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Vogel Ciernia, Annie, Link, Verena M., Careaga, Milo, LaSalle, Janine, Ashwood, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572655/
https://ncbi.nlm.nih.gov/pubmed/32454135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.05.058
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