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Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages

The BTBR T(+)Itpr3(tf)/J (BTBR) mouse has been used as a complex genetic model of Autism Spectrum Disorders (ASD). While the specific mechanisms underlying BTBR behavioral phenotypes are poorly understood, prior studies have implicated profound differences in innate immune system control of pro-infl...

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Détails bibliographiques
Publié dans:Brain Behav Immun
Auteurs principaux: Vogel Ciernia, Annie, Link, Verena M., Careaga, Milo, LaSalle, Janine, Ashwood, Paul
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572655/
https://ncbi.nlm.nih.gov/pubmed/32454135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.05.058
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