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Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes

Developmental programs that generate the astonishing neuronal diversity of the nervous system are not completely understood and thus present a significant challenge for clinical applications of guided cell differentiation strategies. Using direct neuronal programming of embryonic stem cells, we foun...

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發表在:Nat Neurosci
Main Authors: Aydin, Begüm, Kakumanu, Akshay, Rossillo, Mary, Moreno-Estellés, Mireia, Garipler, Görkem, Ringstad, Niels, Flames, Nuria, Mahony, Shaun, Mazzoni, Esteban O.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556771/
https://ncbi.nlm.nih.gov/pubmed/31086315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0399-y
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