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An interpretable bimodal neural network characterizes the sequence and preexisting chromatin predictors of induced transcription factor binding
BACKGROUND: Transcription factor (TF) binding specificity is determined via a complex interplay between the transcription factor’s DNA binding preference and cell type-specific chromatin environments. The chromatin features that correlate with transcription factor binding in a given cell type have b...
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| Publié dans: | Genome Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7788824/ https://ncbi.nlm.nih.gov/pubmed/33413545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02218-6 |
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