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Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity
Efficient transcriptional programming promises to open new frontiers in regenerative medicine. However, mechanisms by which programming factors transform cell fate are unknown, preventing more rational selection of factors to generate desirable cell types. Three transcription factors, Ngn2, Isl1 and...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820498/ https://ncbi.nlm.nih.gov/pubmed/23872598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3467 |
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