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Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

Efficient transcriptional programming promises to open new frontiers in regenerative medicine. However, mechanisms by which programming factors transform cell fate are unknown, preventing more rational selection of factors to generate desirable cell types. Three transcription factors, Ngn2, Isl1 and...

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Bibliografski detalji
Glavni autori: Mazzoni, Esteban O, Mahony, Shaun, Closser, Michael, Morrison, Carolyn A, Nedelec, Stephane, Williams, Damian J, An, Disi, Gifford, David K, Wichterle, Hynek
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820498/
https://ncbi.nlm.nih.gov/pubmed/23872598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3467
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