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A multi-step transcriptional and chromatin state cascade underlies motor neuron programming from embryonic stem cells
Direct cell programming via overexpression of transcription factors (TFs) aims to control cell fate with the degree of precision needed for clinical applications. However, the regulatory steps involved in successful terminal cell fate programming remain obscure. We have investigated the underlying m...
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| Pubblicato in: | Cell Stem Cell |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291817/ https://ncbi.nlm.nih.gov/pubmed/27939218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.11.006 |
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