A multi-step transcriptional and chromatin state cascade underlies motor neuron programming from embryonic stem cells

Direct cell programming via overexpression of transcription factors (TFs) aims to control cell fate with the degree of precision needed for clinical applications. However, the regulatory steps involved in successful terminal cell fate programming remain obscure. We have investigated the underlying m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Stem Cell
Egile Nagusiak: Velasco, Silvia, Ibrahim, Mahmoud M, Kakumanu, Akshay, Garipler, Görkem, Aydin, Begüm, Al-Sayegh, Mohamed Ahmed, Hirsekorn, Antje, Abdul-Rahman, Farah, Satija, Rahul, Ohler, Uwe, Mahony, Shaun, Mazzoni, Esteban O
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291817/
https://ncbi.nlm.nih.gov/pubmed/27939218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.11.006
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