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The N terminus of Ascl1 underlies differing proneural activity of mouse and Xenopus Ascl1 proteins

The proneural basic-helix-loop-helix (bHLH) transcription factor Ascl1 is a master regulator of neurogenesis in both central and peripheral nervous systems in vivo, and is a central driver of neuronal reprogramming in vitro. Over the last three decades, assaying primary neuron formation in Xenopus e...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Hardwick, Laura J.A., Philpott, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182678/
https://ncbi.nlm.nih.gov/pubmed/30363793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14842.1
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