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Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K(+)-Cl(−) Cotransporter KCC2

Chloride (Cl(−)) homeostasis is an essential process involved in neuronal signalling and cell survival. Inadequate regulation of intracellular Cl(−) interferes with synaptic signalling and is implicated in several neurological diseases. The main inhibitory neurotransmitter of the central nervous sys...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Tillman, Luke, Zhang, Jinwei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556333/
https://ncbi.nlm.nih.gov/pubmed/31240228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8941046
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