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Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity
The type II nuclear receptors (NRs) function as heterodimeric transcription factors with the retinoid X receptor (RXR) to regulate diverse biological processes in response to endogenous ligands and therapeutic drugs. DNA-binding specificity has been proposed as a primary mechanism for NR gene regula...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555819/ https://ncbi.nlm.nih.gov/pubmed/31175293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10264-3 |
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