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Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9
Clustered regularly interspaced short palindromic repeat (CRISPR) RNAs and their associated effector (Cas) enzymes are being developed into promising therapeutics to treat disease. However, CRISPR-Cas enzymes might produce unwanted gene editing or dangerous side effects. Drug-like molecules that can...
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| Veröffentlicht in: | Nucleic Acid Ther |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc., publishers
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555185/ https://ncbi.nlm.nih.gov/pubmed/30990769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2018.0758 |
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