OR09-3 11β-HSD1 Mediates a Partial Suppression of Muscle Atrophy in Chronic Inflammatory Disease in Response to Therapeutic Glucocorticoids

Objective: Therapeutic glucocorticoids (GCs) are routinely used in the treatment of chronic inflammatory disease due to their potent anti-inflammatory effects. Despite their efficacy, chronic exposure to GCs elicits undesirable side effects, including muscle atrophy (1). 11 beta-hydroxysteroid dehyd...

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Pubblicato in:J Endocr Soc
Autori principali: Webster, Justine, Fenton, Chloe, Raza, Karim, Lavery, Gareth, Langen, Ramon, Hardy, Rowan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
Soggetti:
Steroid Hormones and Receptors
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554818/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR09-3
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