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A Model for Apoptotic-Cell-Mediated Adaptive Immune Evasion via CD80–CTLA-4 Signaling

Apoptotic cells carry a plethora of self-antigens but they suppress eliciting of innate and adaptive immune responses to them. How apoptotic cells evade and subvert adaptive immune responses has been elusive. Here, we propose a novel model to understand how apoptotic cells regulate T cell activation...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Yakoub, Abraam M., Schülke, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554677/
https://ncbi.nlm.nih.gov/pubmed/31214024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00562
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