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CD28 co-signaling in the adaptive immune response

T-cell proliferation and function depends on signals from the antigen-receptor complex (TCR/CD3) and by various co-receptors such as CD28 and CTLA-4. The balance of positive and negative signals determines the outcome of the T-cell response to foreign and self-antigen. CD28 is a prominent co-recepto...

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Detalhes bibliográficos
Main Authors: Riha, Pavel, Rudd, Christopher E
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047785/
https://ncbi.nlm.nih.gov/pubmed/21487479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.3.12968
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