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CD28 co-signaling in the adaptive immune response
T-cell proliferation and function depends on signals from the antigen-receptor complex (TCR/CD3) and by various co-receptors such as CD28 and CTLA-4. The balance of positive and negative signals determines the outcome of the T-cell response to foreign and self-antigen. CD28 is a prominent co-recepto...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047785/ https://ncbi.nlm.nih.gov/pubmed/21487479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.3.12968 |
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