Human Toll-like Receptor 8 (TLR8) Is an Important Sensor of Pyogenic Bacteria, and Is Attenuated by Cell Surface TLR Signaling

TLR8 is an endosomal sensor of RNA degradation products in human phagocytes, and is involved in the recognition of viral and bacterial pathogens. We previously showed that in human primary monocytes and monocyte derived macrophages, TLR8 senses entire Staphylococcus aureus and Streptococcus agalacti...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Moen, Siv H., Ehrnström, Birgitta, Kojen, June F., Yurchenko, Mariia, Beckwith, Kai S., Afset, Jan E., Damås, Jan K., Hu, Zhenyi, Yin, Hang, Espevik, Terje, Stenvik, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554558/
https://ncbi.nlm.nih.gov/pubmed/31214180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01209
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