Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages

TLR8 is the major endosomal sensor of degraded RNA in human monocytes and macrophages. It has been implicated in the sensing of viruses and more recently also bacteria. We previously identified a TLR8-IFN regulatory factor 5 (IRF5) signaling pathway that mediates IFNβ and interleukin-12 (IL-12) indu...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: Ehrnström, Birgitta, Beckwith, Kai Sandvold, Yurchenko, Mariia, Moen, Siv Helen, Kojen, June Frengen, Lentini, Germana, Teti, Giuseppe, Damås, Jan Kristian, Espevik, Terje, Stenvik, Jørgen
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2017
נושאים:
Immunology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632357/
https://ncbi.nlm.nih.gov/pubmed/29042860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01243
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