Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness

Toll-like receptors (TLRs) are innate immune receptors for sensing microbial molecules and damage-associated molecular patterns released from host cells. Double-stranded RNA and the synthetic analog polyinosinic:polycytidylic acid (poly(I:C)) bind and activate TLR3. This stimulation leads to recruit...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bugge, Marit, Bergstrom, Bjarte, Eide, Oda K., Solli, Helene, Kjønstad, Ingrid F., Stenvik, Jørgen, Espevik, Terje, Nilsen, Nadra J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602399/
https://ncbi.nlm.nih.gov/pubmed/28717003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.784090
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