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Prostaglandin A1 Inhibits the Cognitive Decline of APP/PS1 Transgenic Mice via PPARγ/ABCA1-dependent Cholesterol Efflux Mechanisms

Prostaglandins (PGs) are early and key contributors to chronic neurodegenerative diseases. As one important member of classical PGs, PGA1 has been reported to exert potential neuroprotective effects. However, the mechanisms remain unknown. To this end, we are prompted to investigate whether PGA1 is...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Xu, Guo-Biao, Yang, Liu-Qing, Guan, Pei-Pei, Wang, Zhan-You, Wang, Pu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554490/
https://ncbi.nlm.nih.gov/pubmed/30627958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-00704-1
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