Prostaglandin A1 Inhibits the Cognitive Decline of APP/PS1 Transgenic Mice via PPARγ/ABCA1-dependent Cholesterol Efflux Mechanisms

Prostaglandins (PGs) are early and key contributors to chronic neurodegenerative diseases. As one important member of classical PGs, PGA1 has been reported to exert potential neuroprotective effects. However, the mechanisms remain unknown. To this end, we are prompted to investigate whether PGA1 is...

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Bibliographic Details
Published in:Neurotherapeutics
Main Authors: Xu, Guo-Biao, Yang, Liu-Qing, Guan, Pei-Pei, Wang, Zhan-You, Wang, Pu
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554490/
https://ncbi.nlm.nih.gov/pubmed/30627958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-00704-1
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