Plasminogen promotes cholesterol efflux by the ABCA1 pathway

Using genetic and biochemical approaches, we investigated proteins that regulate macrophage cholesterol efflux capacity (CEC) and ABCA1-specific CEC (ABCA1 CEC), 2 functional assays that predict cardiovascular disease (CVD). Macrophage CEC and the concentration of HDL particles were markedly reduced...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Pamir, Nathalie, Hutchins, Patrick M., Ronsein, Graziella E., Wei, Hao, Tang, Chongren, Das, Riku, Vaisar, Tomas, Plow, Edward, Schuster, Volker, Reardon, Catherine A., Weinberg, Richard, Dichek, David A., Marcovina, Santica, Getz, Godfrey S., Heinecke, Jay W.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543924/
https://ncbi.nlm.nih.gov/pubmed/28768900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92176
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