Plasminogen promotes cholesterol efflux by the ABCA1 pathway

Using genetic and biochemical approaches, we investigated proteins that regulate macrophage cholesterol efflux capacity (CEC) and ABCA1-specific CEC (ABCA1 CEC), 2 functional assays that predict cardiovascular disease (CVD). Macrophage CEC and the concentration of HDL particles were markedly reduced...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Pamir, Nathalie, Hutchins, Patrick M., Ronsein, Graziella E., Wei, Hao, Tang, Chongren, Das, Riku, Vaisar, Tomas, Plow, Edward, Schuster, Volker, Reardon, Catherine A., Weinberg, Richard, Dichek, David A., Marcovina, Santica, Getz, Godfrey S., Heinecke, Jay W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543924/
https://ncbi.nlm.nih.gov/pubmed/28768900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92176
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