Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway

Cholesterol efflux capacity associates strongly and negatively with the incidence and prevalence of human CVD. We investigated the relationships of HDL’s size and protein cargo with its cholesterol efflux capacity using APOB-depleted serum and HDLs isolated from five inbred mouse strains with differ...

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Publicado en:J Lipid Res
Main Authors: Pamir, Nathalie, Hutchins, Patrick, Ronsein, Graziella, Vaisar, Tomas, Reardon, Catherine A., Getz, Godfrey S., Lusis, Aldons J., Heinecke, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2016
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727420/
https://ncbi.nlm.nih.gov/pubmed/26673204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063701
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