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Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway

Cholesterol efflux capacity associates strongly and negatively with the incidence and prevalence of human CVD. We investigated the relationships of HDL’s size and protein cargo with its cholesterol efflux capacity using APOB-depleted serum and HDLs isolated from five inbred mouse strains with differ...

詳細記述

保存先:
書誌詳細
出版年:J Lipid Res
主要な著者: Pamir, Nathalie, Hutchins, Patrick, Ronsein, Graziella, Vaisar, Tomas, Reardon, Catherine A., Getz, Godfrey S., Lusis, Aldons J., Heinecke, Jay W.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727420/
https://ncbi.nlm.nih.gov/pubmed/26673204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063701
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