C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases

C3 glomerulopathy (C3G) is a severe kidney disease, which is caused by defective regulation of the alternative complement pathway. Disease pathogenesis is heterogeneous and is caused by both autoimmune and genetic factors. Here we characterized IgG autoantibodies derived from 33 patients with autoim...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Zhao, Fei, Afonso, Sara, Lindner, Susanne, Hartmann, Andrea, Löschmann, Ina, Nilsson, Bo, Ekdahl, Kristina N., Weber, Lutz T., Habbig, Sandra, Schalk, Gesa, Kirschfink, Michael, Zipfel, Peter F., Skerka, Christine
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554336/
https://ncbi.nlm.nih.gov/pubmed/31214159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01030
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы