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Factor B and C4b2a Autoantibodies in C3 Glomerulopathy

C3 Glomerulopathy (C3G) is a renal disease mediated primarily by dysregulation of the alternative pathway of complement. Complement is the cornerstone of innate immunity. It targets infectious microbes for destruction, clears immune complexes, and apoptotic cells from the circulation, and augments t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hauer, Jill J., Shao, Dingwu, Zhang, Yuzhou, Nester, Carla M., Smith, Richard J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460050/
https://ncbi.nlm.nih.gov/pubmed/31024533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00668
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