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The Tick-Over Theory Revisited: Formation and Regulation of the Soluble Alternative Complement C3 Convertase (C3(H(2)O)Bb)

The molecular interactions between the components of the C3 convertase of the alternative pathway (AP) of complement and its regulators, in both surface-bound and fluid-phase form, are still incompletely understood. The fact that the AP convertase is labile makes studies difficult to perform. Accord...

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Autors principals: Bexborn, Fredrik, Andersson, Per Ola, Chen, Hui, Nilsson, Bo, Ekdahl, Kristina N.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701500/
https://ncbi.nlm.nih.gov/pubmed/18096230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.11.003
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