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The Tick-Over Theory Revisited: Formation and Regulation of the Soluble Alternative Complement C3 Convertase (C3(H(2)O)Bb)

The molecular interactions between the components of the C3 convertase of the alternative pathway (AP) of complement and its regulators, in both surface-bound and fluid-phase form, are still incompletely understood. The fact that the AP convertase is labile makes studies difficult to perform. Accord...

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Bibliografiske detaljer
Main Authors: Bexborn, Fredrik, Andersson, Per Ola, Chen, Hui, Nilsson, Bo, Ekdahl, Kristina N.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701500/
https://ncbi.nlm.nih.gov/pubmed/18096230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.11.003
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