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Enhancement of binding avidity by bivalent binding enables PrP(Sc)-specific detection by anti-PrP monoclonal antibody 132

Anti-prion protein (PrP) monoclonal antibody 132, which recognizes mouse PrP amino acids 119–127, enables us to reliably detect abnormal isoform prion protein (PrP(Sc)) in cells or frozen tissue sections by immunofluorescence assay, although treatment with guanidinium salts is a prerequisite. Despit...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Suzuki, Akio, Yamasaki, Takeshi, Hasebe, Rie, Horiuchi, Motohiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553756/
https://ncbi.nlm.nih.gov/pubmed/31170247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217944
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