SUN-004 Unique Cell Fates and Metastatic Phenotypes Are Activated by Progesterone Receptor (PR) Isoform-specific Gene Expression in Fallopian Tube Models of HGSC

High grade serous ovarian carcinoma (HGSC), the most prevalent and aggressive form of ovarian cancer, contains abundant receptors for the ovarian steroid hormones, estrogen (ER; 76%) and progesterone (PR; 35%). These receptors are known to contribute to breast and reproductive cancer development. Ou...

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Detaylı Bibliyografya
Yayımlandı:J Endocr Soc
Asıl Yazarlar: Seibel, Megan, Spartz, Angela, Drapkin, Ronny, Schwartz, Lauren, Mauro, Laura, Lange, Carol
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2019
Konular:
Steroid Hormones and Receptors
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-004
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