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SUN-004 Unique Cell Fates and Metastatic Phenotypes Are Activated by Progesterone Receptor (PR) Isoform-specific Gene Expression in Fallopian Tube Models of HGSC

High grade serous ovarian carcinoma (HGSC), the most prevalent and aggressive form of ovarian cancer, contains abundant receptors for the ovarian steroid hormones, estrogen (ER; 76%) and progesterone (PR; 35%). These receptors are known to contribute to breast and reproductive cancer development. Ou...

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Vydáno v:J Endocr Soc
Hlavní autoři: Seibel, Megan, Spartz, Angela, Drapkin, Ronny, Schwartz, Lauren, Mauro, Laura, Lange, Carol
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-004
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