SUN-004 Unique Cell Fates and Metastatic Phenotypes Are Activated by Progesterone Receptor (PR) Isoform-specific Gene Expression in Fallopian Tube Models of HGSC

High grade serous ovarian carcinoma (HGSC), the most prevalent and aggressive form of ovarian cancer, contains abundant receptors for the ovarian steroid hormones, estrogen (ER; 76%) and progesterone (PR; 35%). These receptors are known to contribute to breast and reproductive cancer development. Ou...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Endocr Soc
Auteurs principaux: Seibel, Megan, Spartz, Angela, Drapkin, Ronny, Schwartz, Lauren, Mauro, Laura, Lange, Carol
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2019
Sujets:
Steroid Hormones and Receptors
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-004
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