SUN-004 Unique Cell Fates and Metastatic Phenotypes Are Activated by Progesterone Receptor (PR) Isoform-specific Gene Expression in Fallopian Tube Models of HGSC

High grade serous ovarian carcinoma (HGSC), the most prevalent and aggressive form of ovarian cancer, contains abundant receptors for the ovarian steroid hormones, estrogen (ER; 76%) and progesterone (PR; 35%). These receptors are known to contribute to breast and reproductive cancer development. Ou...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Seibel, Megan, Spartz, Angela, Drapkin, Ronny, Schwartz, Lauren, Mauro, Laura, Lange, Carol
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2019
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-004
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