SUN-004 Unique Cell Fates and Metastatic Phenotypes Are Activated by Progesterone Receptor (PR) Isoform-specific Gene Expression in Fallopian Tube Models of HGSC

High grade serous ovarian carcinoma (HGSC), the most prevalent and aggressive form of ovarian cancer, contains abundant receptors for the ovarian steroid hormones, estrogen (ER; 76%) and progesterone (PR; 35%). These receptors are known to contribute to breast and reproductive cancer development. Ou...

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Publicat a:J Endocr Soc
Autors principals: Seibel, Megan, Spartz, Angela, Drapkin, Ronny, Schwartz, Lauren, Mauro, Laura, Lange, Carol
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Steroid Hormones and Receptors
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-004
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