An apically located hybrid guanylate cyclase–ATPase is critical for the initiation of Ca(2+) signaling and motility in Toxoplasma gondii

Protozoan parasites of the phylum Apicomplexa actively move through tissue to initiate and perpetuate infection. The regulation of parasite motility relies on cyclic nucleotide-dependent kinases, but how these kinases are activated remains unknown. Here, using an array of biochemical and cell biolog...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Luning, Uboldi, Alessandro D., Seizova, Simona, Wilde, Mary-Louise, Coffey, Michael J., Katris, Nicholas J., Yamaryo-Botté, Yoshiki, Kocan, Martina, Bathgate, Ross A. D., Stewart, Rebecca J., McConville, Malcolm J., Thompson, Philip E., Botté, Cyrille Y., Tonkin, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552420/
https://ncbi.nlm.nih.gov/pubmed/30992368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005491
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