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Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii

Toxoplasma gondii proliferates within host cell vacuoles where the parasite relies on host carbon and nutrients for replication. To assess how T. gondii utilizes these resources, we mapped the carbon metabolism pathways in intracellular and egressed parasite stages. We determined that intracellular...

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Autores principales: MacRae, James I., Sheiner, Lilach, Nahid, Amsha, Tonkin, Christopher, Striepen, Boris, McConville, Malcolm J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990185/
https://ncbi.nlm.nih.gov/pubmed/23159057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.09.013
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