Caricamento...

Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase

Alzheimer´s disease (AD) is a devastating neurodegenerative disease of the elderly population. Genetic evidence strongly suggests that aberrant generation and/or clearance of the neurotoxic amyloid-β peptide (Aβ) is triggering the disease. Aβ is generated from the amyloid precursor protein (APP) by...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Stress
Autori principali: Steiner, Harald, Fukumori, Akio, Tagami, Shinji, Okochi, Masayasu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shared Science Publishers OG 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551803/
https://ncbi.nlm.nih.gov/pubmed/31225454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.11.162
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !