SAT-260 Selective Nonpeptide Somatostatin Subtype 5 (sst5) Agonists Suppress Induced Insulin Secretion in Pancreatic Islets from both Rats and Healthy Human Donors

Hyperinsulinemia is a heterogeneous condition in which dangerously low blood sugar levels are caused by improperly regulated insulin secretion from pancreatic ß-cells. The most severe form of hyperinsulinemia arises from congenital hyperinsulinism (CHI), a set of genetic disorders in which the under...

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Vydáno v:J Endocr Soc
Hlavní autoři: Rico-Bautista, Elizabeth, Kusnetzow, Ana, Fowler, Melissa, Athanacio, Jon, Kredel, Taylor, Zhao, Jian, Wang, Shimiao, Markison, Stacy, Zhu, Yun Fei, Struthers, Scott, Betz, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
Pediatric Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551644/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-260
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