Transcytosis maintains CFTR apical polarity in the face of constitutive and mutation-induced basolateral missorting

Apical polarity of cystic fibrosis transmembrane conductance regulator (CFTR) is essential for solute and water transport in secretory epithelia and can be impaired in human diseases. Maintenance of apical polarity in the face of CFTR non-polarized delivery and inefficient apical retention of mutant...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Bidaud-Meynard, Aurélien, Bossard, Florian, Schnúr, Andrea, Fukuda, Ryosuke, Veit, Guido, Xu, Haijin, Lukacs, Gergely L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550009/
https://ncbi.nlm.nih.gov/pubmed/30975917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.226886
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