Transcytosis maintains CFTR apical polarity in the face of constitutive and mutation-induced basolateral missorting

Apical polarity of cystic fibrosis transmembrane conductance regulator (CFTR) is essential for solute and water transport in secretory epithelia and can be impaired in human diseases. Maintenance of apical polarity in the face of CFTR non-polarized delivery and inefficient apical retention of mutant...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Bidaud-Meynard, Aurélien, Bossard, Florian, Schnúr, Andrea, Fukuda, Ryosuke, Veit, Guido, Xu, Haijin, Lukacs, Gergely L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550009/
https://ncbi.nlm.nih.gov/pubmed/30975917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.226886
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky