Transcytosis maintains CFTR apical polarity in the face of constitutive and mutation-induced basolateral missorting

Apical polarity of cystic fibrosis transmembrane conductance regulator (CFTR) is essential for solute and water transport in secretory epithelia and can be impaired in human diseases. Maintenance of apical polarity in the face of CFTR non-polarized delivery and inefficient apical retention of mutant...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Cell Sci
Autores principales: Bidaud-Meynard, Aurélien, Bossard, Florian, Schnúr, Andrea, Fukuda, Ryosuke, Veit, Guido, Xu, Haijin, Lukacs, Gergely L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550009/
https://ncbi.nlm.nih.gov/pubmed/30975917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.226886
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares