High-throughput microscopy exposes a pharmacological window in which dual leucine zipper kinase inhibition preserves neuronal network connectivity

Therapeutic developments for neurodegenerative disorders are redirecting their focus to the mechanisms that contribute to neuronal connectivity and the loss thereof. Using a high-throughput microscopy pipeline that integrates morphological and functional measurements, we found that inhibition of dua...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Verschuuren, Marlies, Verstraelen, Peter, García-Díaz Barriga, Gerardo, Cilissen, Ines, Coninx, Emma, Verslegers, Mieke, Larsen, Peter H., Nuydens, Rony, De Vos, Winnok H.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549294/
https://ncbi.nlm.nih.gov/pubmed/31164177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0741-3
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki