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Systematic Quantification of Synapses in Primary Neuronal Culture

Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve synapse-oriented screens, we analyzed the labeling performance o...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Verstraelen, Peter, Garcia-Diaz Barriga, Gerardo, Verschuuren, Marlies, Asselbergh, Bob, Nuydens, Rony, Larsen, Peter H., Timmermans, Jean-Pierre, De Vos, Winnok H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516133/
https://ncbi.nlm.nih.gov/pubmed/33083769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101542
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