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Systematic Quantification of Synapses in Primary Neuronal Culture

Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve synapse-oriented screens, we analyzed the labeling performance o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:iScience
Egile Nagusiak: Verstraelen, Peter, Garcia-Diaz Barriga, Gerardo, Verschuuren, Marlies, Asselbergh, Bob, Nuydens, Rony, Larsen, Peter H., Timmermans, Jean-Pierre, De Vos, Winnok H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516133/
https://ncbi.nlm.nih.gov/pubmed/33083769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101542
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