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Systematic Quantification of Synapses in Primary Neuronal Culture

Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve synapse-oriented screens, we analyzed the labeling performance o...

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Bibliografski detalji
Izdano u:iScience
Glavni autori: Verstraelen, Peter, Garcia-Diaz Barriga, Gerardo, Verschuuren, Marlies, Asselbergh, Bob, Nuydens, Rony, Larsen, Peter H., Timmermans, Jean-Pierre, De Vos, Winnok H.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516133/
https://ncbi.nlm.nih.gov/pubmed/33083769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101542
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