Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds

Heparanase is an endoglycosidase involved in remodeling the extracellular matrix and thereby in regulating multiple cellular processes and biological activities. It cleaves heparan sulfate (HS) side chains of HS proteoglycans into smaller fragments and hence regulates tissue morphogenesis, different...

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Detaylı Bibliyografya
Yayımlandı:iScience
Asıl Yazarlar: Mohan, Chakrabhavi Dhananjaya, Hari, Swetha, Preetham, Habbanakuppe D., Rangappa, Shobith, Barash, Uri, Ilan, Neta, Nayak, S. Chandra, Gupta, Vijai K., Basappa, Vlodavsky, Israel, Rangappa, Kanchugarakoppal S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548846/
https://ncbi.nlm.nih.gov/pubmed/31103854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.04.034
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