Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys with Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is an inherited neuromuscular disorder occurring in boys and caused by mutations in the dystrophin gene. Vamorolone is a first-generation delta-9,11 compound that has favorable efficacy and side effect profiles relative to classical glucocorticoids. The pharmacokine...

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Udgivet i:J Clin Pharmacol
Main Authors: Mavroudis, Panteleimon D., van den Anker, John, Conklin, Laurie S., Damsker, Jesse M., Hoffman, Eric P., Nagaraju, Kanneboyina, Clemens, Paula R., Jusko, William J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548694/
https://ncbi.nlm.nih.gov/pubmed/30742306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1388
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