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A Precision B cell-targeted Therapeutic Approach to Autoimmunity Caused by PI3K Pathway Dysregulation
The inositol lipid phosphatases, PTEN and SHIP-1 play a crucial role in maintaining B cell anergy and are reduced in expression in B cells from SLE and T1D patients, consequent to aberrant regulation by miRNA-7 and 155. With an eye towards eventual use in precision medicine therapeutic approaches in...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548689/ https://ncbi.nlm.nih.gov/pubmed/31076529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801394 |
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