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Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma
The phosphoinositide 3-kinase (PI3K) signaling pathway is the most commonly mutated pathway in head and neck squamous cell carcinoma (HNSCC). There are several drugs targeting members of the PI3K signaling pathway in development for HNSCC. In this article, we review the genetic alterations reported...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400658/ https://ncbi.nlm.nih.gov/pubmed/28108737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14729 |
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