Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma

The phosphoinositide 3-kinase (PI3K) signaling pathway is the most commonly mutated pathway in head and neck squamous cell carcinoma (HNSCC). There are several drugs targeting members of the PI3K signaling pathway in development for HNSCC. In this article, we review the genetic alterations reported...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Cai, Yi, Dodhia, Sonam, Su, Gloria H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400658/
https://ncbi.nlm.nih.gov/pubmed/28108737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14729
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