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Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma

The phosphoinositide 3-kinase (PI3K) signaling pathway is the most commonly mutated pathway in head and neck squamous cell carcinoma (HNSCC). There are several drugs targeting members of the PI3K signaling pathway in development for HNSCC. In this article, we review the genetic alterations reported...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Cai, Yi, Dodhia, Sonam, Su, Gloria H
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400658/
https://ncbi.nlm.nih.gov/pubmed/28108737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14729
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